Vitro Comparison of the Antimicrobial Activity of Honey - Nursing Assignment Help

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The main line of treatment for chronic wounds is the application of an appropriate dressing. Dressings can be used to reduce odour and pain, maintain a moist healing environment, remove excessive exudate and prevent clinical infection. Antimicrobial compounds such as silver, honey and iodine have been in use for millennia. The discovery of antibiotics in the early 20th century gready reduced the routine usage of such compounds. More recently, there has been renewed interest in these compounds, with manufacturers adding these to dressings to provide greater antimicrobial action and aid the healing process. Much of the published literature on the antimicrobial prop-erties of silver, honey and iodine-containing dressings is contradictory, with varying degrees of efficacy reported. This study aimed to independently compare the in vitro antimicrobial activity of a wide variety of dressings against common wound pathogens; Escherichia col, Staphylococcus aureus and Pseudomonas aeruginosa, in order to provide further evidence and aid dressing selection. Although no significant differences were reported between honey, iodine and sive, a significant difference was observed between the individual dressings, indicating that determination of bacterial species present within a wound can aid cinical staff in the selection of the most appropriate dressing.Introduction occlusion or high external pressure, all resulting in local tissue hypoxia, cell dysfunction and deaths Many patients Wound classification develop predispositions to delayed healing with increasing d i ti chronic A wound may be defined as a breach in the epidermis or dermis, due to trauma or physiological change, activating the repair process.' Wounds can be classified as either acute or chronic. An acute wound will heal as expected, usually within a relatively short time with few complications, for example, a surgical wound. In comparison, chronic wounds fail to heal as expected or become fixed at one pha. of wound healing for a period greater than 6 weeks.• This characteristic prolonged healing period is accompanied by inflammation, increased wound exudate and compli-cations such as infection? Examples of chronic wounds include: pressure ulcers, venous, arterial and diabetic ulcers. Such wotmds involve patient-specific factors that pre-dispose individuals to develop poorly healing wounds, for example, venous insufficiency, diabetes mellitus, arteriala on c ron c woun s are quent y seen Acute wounds, us:Illinzquire little intervention and heal ram tlyf Therefore e, wounds and some article details the manage-theoase WI:heirZ.:bee:1 or sac:: cr:cao7fbbe:roan;airc:ffiecc::1). Management of these highly complex wounds is Ia bour intensive and costly to treat..cations for the National Health Service (NHS, Wound Infection The moist environment of chronic wounds is an ideal growth medium for bacteria° and infection is the prominent cause of 
 

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