DIP303: Drugs and Integrated Pharmacology-Report Writing - Medical Science Assignment Help

Assignment Task

Part A: Answer the following – Body of Report

1. Evaluate available research and provide a brief summary of the pathophysiology of osteoarthritis (OA) also explaining the aetiology and manifestations. Referencing required

2. Discuss the use of paracetamol in OA including its mechanism of action and any cautions with its use. Explain the pharmacokinetic differences between regular Panadol® tablets and Pandol Osteo®? Could Marta use either? Referencing and clinical judgement required A friend of Marta’s recently suggested that she try Nurofen Plus ® for pain as she said it had helped her back pain and Marta asks for your advice.

3. What does Nurofen Plus contain? Is it indicated for osteoarthritis? Referencing required

4. Considering all aspects of Marta’s history do you think the Nurofen Plus is appropriate? What would you recommend she do with regards to managing his symptoms and medications? Clinical judgement

5. Given the availability of NSAIDs over the counter (OTC), what general safety considerations should patients be aware of? Referencing required

6. Consider your initial & brief treatment plan (based on your modality) you need to be able to answer the following;

a. Are there any drug/drug/herb/nutrient/massage interactions or drug side effects that Marta may experience? (You need to consider before treating Marta given her medications and history, to ensure safe practices.)

b. Would you refer her back to his GP and why/why not? Clinical judgement

Part B: Answer the following – Body or Report

7. Discuss the use of statins in hypercholesterolemia including the mechanism of action, routes of administration and considerations around safety, side effects and complications, in particular for someone like Marta. Referencing required

8. Since you last saw her, Marta has changed a number of her medications including several that can have an effect on bone density and on myalgia. For the following prescribed medicines, Fosamax, Prednisone and Lasix: a) Explain the pharmacodynamics of each. Referencing required b) Discuss any potential for interactions and adverse effects with this combination. Referencing required c) Are there any concerns and if so, how would you act? Clinical judgement

9. Discuss altered pharmacokinetics in an elderly person, using Marta and her current medication regime to explain the factors that need to be considered when prescribing to this population group. Referencing required

10. Choose ONE of the following drugs – Tramadol, Fosamax, Lovastatin ? and complete a brief drug monograph using the template provided. This monograph should be attached as an appendix (wont contribute to the word count). Referencing required

11. For the drug that you chose above, do a literature search and review 2 of the most recent and highest evidence studies you can find for that drug. The aim of the review is to see if there is any new information available with regards to the use of this drug that will help you treating Marta. For example, adverse effects due to long term use, information on an interaction or perhaps increased effectiveness when used in combination with something else. You should provide a brief summary paragraph with regards to the type of study, its outcomes and the validity of the study. Referencing required

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